Sounds like something to be spread on dry toast and choked down between sobs.
Means "world-weariness", or "the kind of feeling experienced by someone who understands that physical reality can never satisfy the demands of the mind". Boy does it never.
I need things like this in my vocabulary; just knowing there's a word for it makes so many things so much better.
Also a favorite because it has a sort of a phlegm sound in it.